New published article: Chantrain et al., 2023

Congratulations to Dr. Chantrain and colleagues on the publication of their article on the study of joint status, pain, and quality of life in elderly people with hemophilia in the journal Haemophilia. We are proud to have contributed to the success of this article!

Elderly patients with hemophilia can suffer from 𝐡𝐞𝐦𝐨𝐩𝐡𝐢𝐥𝐢𝐜 𝐚𝐫𝐭𝐡𝐫𝐨𝐩𝐚𝐭𝐡𝐲, due to recurrent hemarthrosis. 𝐇𝐞𝐦𝐚𝐫𝐭𝐡𝐫𝐨𝐬𝐢𝐬 refers to an 𝐞𝐟𝐟𝐮𝐬𝐢𝐨𝐧 𝐨𝐟 𝐛𝐥𝐨𝐨𝐝 into a joint, resulting in joint tissue damage, pain, and reduced quality of life (QoL). To this day, these elements have rarely been assessed in 𝐞𝐥𝐝𝐞𝐫𝐥𝐲 𝐩𝐞𝐨𝐩𝐥𝐞 𝐰𝐢𝐭𝐡 𝐦𝐢𝐥𝐝 𝐡𝐞𝐦𝐨𝐩𝐡𝐢𝐥𝐢𝐚. This study compared 𝐣𝐨𝐢𝐧𝐭 𝐜𝐨𝐧𝐝𝐢𝐭𝐢𝐨𝐧, 𝐩𝐚𝐢𝐧, 𝐚𝐧𝐝 𝐐𝐨𝐋 between healthy elderly patients and patients with mild or moderate/severe hemophilia.

The authors recruited 40 individuals with hemophilia (mild: 23 patients and moderate/severe: 17 patients) over 60 years of age and 20 age-matched controls. Patients with moderate/severe hemophilia had 𝐣𝐨𝐢𝐧𝐭𝐬 (knees and ankles) in 𝐰𝐨𝐫𝐬𝐞 𝐜𝐨𝐧𝐝𝐢𝐭𝐢𝐨𝐧 on ultrasound, 𝐥𝐨𝐰𝐞𝐫 𝐩𝐫𝐞𝐬𝐬𝐮𝐫𝐞 𝐩𝐚𝐢𝐧 𝐭𝐡𝐫𝐞𝐬𝐡𝐨𝐥𝐝𝐬, and a 𝐥𝐨𝐰𝐞𝐫 𝐐𝐨𝐋 than patients with mild hemophilia and healthy subjects. Some patients with mild hemophilia also experienced functional and QoL impairments, but comparisons with healthy subjects were not significant.

Although these results need to be confirmed by studies with larger numbers of patients, these findings on 𝐟𝐚𝐜𝐭𝐨𝐫𝐬 𝐚𝐬𝐬𝐨𝐜𝐢𝐚𝐭𝐞𝐝 𝐰𝐢𝐭𝐡 𝐩𝐚𝐢𝐧 𝐢𝐧 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐰𝐢𝐭𝐡 𝐡𝐞𝐦𝐨𝐩𝐡𝐢𝐥𝐢𝐚 are very interesting and require further investigation. The article is already available on the journal's website! 𝐃𝐎𝐈: 𝟏𝟎.𝟏𝟏𝟏𝟏/𝐡𝐚𝐞.𝟏𝟒𝟖𝟗𝟎